Human Interferon Lambda-1, IFNL1 Primacu™ ELI
3,970.00 ₪
Interleukin-29 (IL-29), also known as cytokine Zcyto21, Interferon lambda-1, IFN-lambda-1, and IFNL1, is a secreted protein that belongs to the IL-28 / IL-29 family.
IL-29 is a cytokine with immunomodulatory activity.
IL-29 is highly similar in amino acid sequence to the IL-28.
IL-28 and IL-29 are induced by a viral infection and showed antiviral activity.
IL-28 and IL-29 interacted with a heterodimeric class II cytokine receptor that consisted of IL-10 receptor beta (IL-10Rbeta) and an orphan class II receptor chain, designated IL-28Ralpha.
IL-29 plays an important role in host defenses against microbes and its gene is highly upregulated in cells infected with viruses.
IL-29 may play a role in antiviral immunity.
IL-29 up-regulates MHC class I antigen expression.
It is a Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA.
The ligand/receptor complex seems to signal through the Jak-STAT pathway.
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