Human Interleukin-1 Family Member 10, IL1F10 ELI

Cytokine with immunomodulatory activity.

Alone, does not induce cytokine production, but reduces IL22 and IL17A production by T-cells in response to heat-killed Candida albicans.

Reduces IL36G-induced production of IL8 by peripheral blood mononuclear cells.

Increases IL6 production by dendritic cells stimulated by bacterial lipopolysaccharides (LPS).

Ligand for IL-36R/IL1RL2.