Human Interleukin 12 Receptor Subunit Beta-1, IL12RB1 ELI

Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction.

Associated with IL12RB2 it forms a functional, high affinity receptor for IL12.

Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.