Human Interleukin-13, IL13 Primacu™ ELI
3,970.00 ₪
Interleukin 13 (IL-13) is a single-chain glycosylated polypeptide, which belongs to the IL-13/IL-4 family.
IL-13 protein is secreted by many cell types, but especially by T helper type 2 (Th2) cells.
IL-13 exerts its effects through a multi-subunit receptor comprising the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains (IL-13 Rα1 and IL-13 Rα2).
As a cytokine, IL-13 protein is critical in regulating inflammatory, immune responses, and diseases.
Also, it inhibits the production of pro-inflammatory cytokines and chemokines, and thus down-regulates macrophage activity.
IL-13 protein and antibody are more importantly implicated as a central mediator of immunoregulatory processes in various cell types.
Cancer Immunotherapy Immune Checkpoint Immunotherapy Targeted Therapy
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