Human Interleukin 21 Receptor, IL21R ELI

Interleukin 21 receptor is a type I cytokine receptor.

IL21R is its human gene.

The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21).

It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2 (IL2), interleukin 7 (IL7) and interleukin 15 (IL15).

This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells.