Human Interleukin 24, IL-24 ELI
3,140.00 ₪
Interleukin 24 (IL-24) is a protein in the interleukin family, a type of cytokine signaling molecule in the immune system.
In humans, this protein is encoded by the IL24 gene.
IL-24 is a cytokine belonging to the IL-10 family of cytokines that signals through two heterodimeric receptors: IL-20R1/IL-20R2 and IL-22R1/IL-20R2.
This interleukin is also known as melanoma differentiation-associated 7 (mda-7) due to its discovery as a tumour suppressing protein.
IL-24 appears to control cell survival and proliferation by inducing rapid activation of particular transcription factors called STAT1 and STAT3.
This cytokine is predominantly released by activated monocytes, macrophages and T helper 2 (Th2) cells[5] and acts on skin, lung, and reproductive tissues.
IL-24 performs important roles in wound healing, arthritis, psoriasis and cancer.
Several studies have shown that cell death occurs in cancer cells/cell lines following exposure to IL-24.
The gene for IL-24 is located on chromosome 1 in humans.
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