Human Kinesin-1 Heavy Chain, KIF5B ELI

Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes.

Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner (By similarity).

Regulates centrosome and nuclear positioning during mitotic entry.

During the G2 phase of the cell cycle in a BICD2-dependent manner, antagonizes dynein function and drives the separation of nuclei and centrosomes (PubMed: 20386726).

Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation (By similarity).