Human Kynurenine/Alpha-aminoadipate Aminotransferase, AADAT ELI

Transaminase with broad substrate specificity.

Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate.

Shows activity also towards tryptophan, aspartate and hydroxykynurenine.

Accepts a variety of oxo-acids as amino-group acceptors, with a preference for 2-oxoglutarate, 2-oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid.

Can also use glyoxylate as amino-group acceptor (in vitro).