Human Leukocyte-specific Transcript 1 Protein, LST1 ELI

Possible role in modulating immune responses.

Induces morphological changes including production of filopodia and microspikes when overexpressed in a variety of cell types and may be involved in dendritic cell maturation.

Isoform 1 and isoform 2 have an inhibitory effect on lymphocyte proliferation.