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Human Long-chain-fatty-acid--CoA ligase 4,ACSL4 ELI

Price

‏3,140.00 ‏₪

Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoA for both synthesis of cellular lipids, and degradation via beta-oxidation (PubMed:24269233, PubMed:22633490, PubMed:21242590).

Preferentially activates arachidonate and eicosapentaenoate as substrates (PubMed:21242590).

Preferentially activates 8,9-EET > 14,15-EET > 5,6-EET > 11,12-EET.

Modulates glucose-stimulated insulin secretion by regulating the levels of unesterified EETs (By similarity).

Modulates prostaglandin E2 secretion (PubMed:21242590).

{ECO:0000250|UniProtKB:O35547, ECO:0000269|PubMed:21242590, ECO:0000269|PubMed:22633490, ECO:0000269|PubMed:24269233}.

Package Size

Quantity

Storage and Stability

2-8ºC

Sensitivity

0.14ng/ml

Detection range

0.25-16ng/ml

Shipping Conditions

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