Human Long-chain Fatty Acid Transport Protein 1, SLC27A1 ELI
3,140.00 ₪
Mediates the ATP-dependent import of long-chain fatty acids (LCFA) into the cell by mediating their translocation at the plasma membrane (PubMed: 28178239).
Has also an acyl-CoA ligase activity for long-chain and very-long-chain fatty acids.
May act directly as a bona fide transporter, or alternatively, in a cytoplasmic or membrane-associated multimeric protein complex to trap and draw fatty acids towards accumulation.
Plays a pivotal role in regulating available LCFA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis.
May be involved in regulation of cholesterol metabolism (By similarity).
Probably involved in fatty acid transport across the blood barrier (PubMed: 21395585).
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