Human Mannose-binding Protein C, MBL2 ELI

Calcium-dependent lectin involved in innate immune defense.

Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway.

Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages.

May bind DNA.