Human Marginal zone B- and B1-cell-specific protein,MZB1 ELI
3,140.00 ₪
Associates with immunoglobulin M (IgM) heavy and light chains and promotes IgM assembly and secretion.
May exert its effect by acting as a molecular chaperone or as an oxidoreductase as it displays a low level of oxidoreductase activity (By similarity).
Isoform 2 may be involved in regulation of apoptosis.
Helps to diversify peripheral B-cell functions by regulating Ca(2+) stores, antibody secretion and integrin activation.
{ECO:0000250, ECO:0000269|PubMed:11350957, ECO:0000269|PubMed:21688198}.; Acts as a hormone-regulated adipokine/proinflammatory cytokine that is implicated in causing chronic inflammation, affecting cellular expansion and blunting insulin response in adipocytes.
May have a role in the onset of insulin resistance.
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