Human Melanocyte Protein Pmel, SILV ELI

Plays a central role in the biogenesis of melanosomes.

Involved in the maturation of melanosomes from stage I to II.

The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures.

Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity.