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Human Meprin A Subunit Beta, MEP1B ELI

Price

‏3,140.00 ‏₪

Membrane metallopeptidase that sheds many membrane-bound proteins.

Exhibits a strong preference for acidic amino acids at the P1' position.

Known substrates include: FGF19, VGFA, IL1B, IL18, procollagen I and III, E-cadherin, KLK7, gastrin, ADAM10, tenascin-C.

The presence of several pro-inflammatory cytokine among substrates implicate MEP1B in inflammation.

It is also involved in tissue remodeling due to its capability to degrade extracellular matrix components.

Package Size

Quantity

Storage and Stability

2-8ºC

Sensitivity

0.027ng/mL

Detection range

0.05-20ng/mL

Shipping Conditions

Next Day Ambient
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