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Human Metalloprotease TIKI1,TRABD2A ELI
Price
3,140.00 ₪
Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the 8 N-terminal residues of a subset of Wnt proteins.
Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation.
Able to cleave WNT3A, WNT5, but not WNT11.
Required for head formation.
{ECO:0000269|PubMed:22726442}.
Quantity
Storage and Stability
2-8ºC
Sensitivity
0.12ng/ml
Detection range
0.25-16ng/ml
Shipping Conditions
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