Human Methionyl Aminopeptidase 1, METAP1 ELI

Cotranslationally removes the N-terminal methionine from nascent proteins.

The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

Required for normal progression through the cell cycle.