Human Milk Fat Globule-egf Factor 8 Protein,MFGE8 ELI

Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing.

Promotes VEGF-dependent neovascularization (By similarity).

Contributes to phagocytic removal of apoptotic cells in many tissues.

Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors.

Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner.

Zona pellucida-binding protein which may play a role in gamete interaction.

{ECO:0000250, ECO:0000269|PubMed:19204935}.; [Medin]: Main constituent of aortic medial amyloid.

{ECO:0000269|PubMed:19204935}.