Human Mitochondrial Fission 1 Protein, FIS1 ELI

Involved in the fragmentation of the mitochondrial network and its perinuclear clustering.

Plays a minor role in the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission.

Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis.

Also mediates peroxisomal fission.