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Human N-lysine Methyltransferase Smyd2, SMYD2 ELI

Price

‏3,140.00 ‏₪

Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1.

Specifically trimethylates histone H3 'Lys-4' (H3K4me3) in vivo.

The activity requires interaction with HSP90alpha.

Shows even higher methyltransferase activity on p53/TP53.

Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53.

Monomethylates RB1 at 'Lys-860'.

Package Size

Quantity

Storage and Stability

2-8ºC

Sensitivity

7.18ng/L

Detection range

15-3000ng/L

Shipping Conditions

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