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Human Nicastrin, NCSTN ELI

Price

‏3,140.00 ‏₪

Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein) (PubMed: 10993067, PubMed: 12679784, PubMed: 25043039, PubMed: 26280335, PubMed: 30598546, PubMed: 30630874).

The gamma-secretase complex plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels.

Package Size

Quantity

Storage and Stability

2-8ºC

Sensitivity

7.28ng/L

Detection range

15-3000ng/L

Shipping Conditions

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