Human Nuclear receptor subfamily 4 group A member 1 ,NR4A1 ELI

Orphan nuclear receptor.

May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration.

Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' (By similarity).

May inhibit NF-kappa-B transactivation of IL2.

Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation.

Plays a role in the vascular response to injury (By similarity).

{ECO:0000250, ECO:0000250|UniProtKB:P12813, ECO:0000269|PubMed:15466594, ECO:0000269|PubMed:22983157}.