Human Otolin 1, OTOL1 ELI

Collagen-like protein specifically expressed in the inner ear, which provides an organic scaffold for otoconia, a calcium carbonate structure in the saccule and utricle of the ear.

Acts as a scaffold for biomineralization: sequesters calcium and forms interconnecting fibrils between otoconia that are incorporated into the calcium crystal structure.

Together with OC90, modulates calcite crystal morphology and growth kinetics.