Human Peroxisome Proliferator Activated Receptor Delta, PPARD ELI

Ligand-activated transcription factor.

Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids.

Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid.

Once activated by a ligand, the receptor binds to promoter elements of target genes.

Regulates the peroxisomal beta-oxidation pathway of fatty acids.

Functions as transcription activator for the acyl-CoA oxidase gene.

Decreases expression of NPC1L1 once activated by a ligand.