Human Platelet Factor 4, PF-4 ELI

Released during platelet aggregation.

Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule.

Chemotactic for neutrophils and monocytes.

Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form.