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Human Probable G-protein coupled receptor 52,GPR52 ELI

Price

‏3,140.00 ‏₪

Gs-coupled receptor activated by antipsychotics reserpine leading to an increase in intracellular cAMP and its internalization (PubMed:24587241).

May play a role in locomotor activity through modulation of dopamine, NMDA and ADORA2A-induced locomotor activity.

These behavioral changes are accompanied by modulation of the dopamine receptor signaling pathway in striatum (PubMed:24587241).

Modulates HTT level via cAMP-dependent but PKA independent mechanisms throught activation of RAB39B that translocates HTT to the endoplasmic reticulum, thus avoiding proteasome degradation (PubMed:25738228).

{ECO:0000269|PubMed:24587241, ECO:0000269|PubMed:25738228}.

Package Size

Quantity

Storage and Stability

2-8ºC

Sensitivity

9.39ng/L

Detection range

20-3800ng/L

Shipping Conditions

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