Human Proenkephalin-B,PDYN ELI

Leu-enkephalins compete with and mimic the effects of opiate drugs.

They play a role in a number of physiologic functions, including pain perception and responses to stress (By similarity).

{ECO:0000250}.; Dynorphin peptides differentially regulate the kappa opioid receptor.

Dynorphin A(1-13) has a typical opiod activity, it is 700 times more potent than Leu-enkephalin (By similarity).

{ECO:0000250}.; Leumorphin has a typical opiod activity and may have anti-apoptotic effect.

{ECO:0000250}.