Human Prostate-Specific Antigen, KLK3 Primacu™ ELI

KLK3 (Kallikrein Related Peptidase 3) is a Protein Coding gene.

The gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19.

It encodes a single-chain glycoprotein, a protease that is synthesized in the epithelial cells of the prostate gland and is present in seminal plasma.

KLK3, also known as Prostate Specific Antigen (PSA), kallikrein-related peptidase 3, Gamma-seminoprotein, is a secreted protein of the glandular kallikrein subfamily of serine proteases.

KLK3 contains one peptidase S1 domain.

KLK3 is a glycoprotein produced almost exclusively by the prostate gland.

Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers.

Cancer Immunotherapy Immune Checkpoint Immunotherapy Targeted Therapy