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Human Proto-Oncogene Mas,MAS1 ELI

Price

‏3,140.00 ‏₪

Receptor for angiotensin 1-7 (By similarity).

Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels.

Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade.

The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1.

{ECO:0000250, ECO:0000269|PubMed:15809376, ECO:0000269|PubMed:16611642}.

Package Size

Quantity

Storage and Stability

2-8ºC

Sensitivity

6.31ng/L

Detection range

15-3000ng/L

Shipping Conditions

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