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Human Receptor tyrosine-protein kinase erbB-3,ERBB3 ELI

Price

‏3,140.00 ‏₪

Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins.

Binds to neuregulin-1 (NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase (PubMed:20682778).

May also be activated by CSPG5 (PubMed:15358134).

Involved in the regulation of myeloid cell differentiation (PubMed:27416908).

{ECO:0000269|PubMed:15358134, ECO:0000269|PubMed:20682778, ECO:0000269|PubMed:27416908}.

Package Size

Quantity

Storage and Stability

2-8ºC

Sensitivity

0.014ng/ml

Detection range

0.05-15ng/ml

Shipping Conditions

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