Human Reticulon-4 Receptor-like 2, RTN4RL2 ELI
3,140.00 ₪
Cell surface receptor that plays a functionally redundant role in the inhibition of neurite outgrowth mediated by MAG (By similarity).
Plays a functionally redundant role in postnatal brain development.
Contributes to normal axon migration across the brain midline and normal formation of the corpus callosum.
Does not seem to play a significant role in regulating axon regeneration in the adult central nervous system.
Protects motoneurons against apoptosis; protection against apoptosis is probably mediated by MAG (By similarity).
Like other family members, plays a role in restricting the number dendritic spines and the number of synapses that are formed during brain development (PubMed: 22325200).
Signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton (PubMed: 22325200).
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