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Human SAM and SH3 domain-containing 1,SASH1 ELI

Price

‏3,140.00 ‏₪

Is a positive regulator of NF-kappa-B signaling downstream of TLR4 activation.

It acts as a scaffold molecule to assemble a molecular complex that includes TRAF6, MAP3K7, CHUK and IKBKB, thereby facilitating NF-kappa-B signaling activation (PubMed:23776175).

Regulates TRAF6 and MAP3K7 ubiquitination (PubMed:23776175).

Involved in the regulation of cell mobility (PubMed:23333244, PubMed:23776175, PubMed:25315659).

Regulates lipolysaccharide (LPS)-induced endothelial cell migration (PubMed:23776175).

Is involved in the regulation of skin pigmentation through the control of melanocyte migration in the epidermis (PubMed:23333244).

{ECO:0000269|PubMed:23333244, ECO:0000269|PubMed:23776175, ECO:0000269|PubMed:25315659}.

Package Size

Quantity

Storage and Stability

2-8ºC

Sensitivity

0.102ng/ml

Detection range

0.2-60ng/ml

Shipping Conditions

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