Human Selenium-binding Protein 1, SELENBP1 ELI

Modulates calcium-dependent activity of inositol 1,4,5-triphosphate receptors (ITPRs)(PubMed: 14570872).

Inhibits agonist-induced intracellular calcium signaling (PubMed: 15980432).

Enhances inactivation and does not support calcium-dependent facilitation of voltage-dependent P/Q-type calcium Channels (PubMed: 11865310).

Causes calcium-dependent facilitation and inhibits inactivation of L-type calcium Channels by binding to the same sites as calmodulin in the C-terminal domain of CACNA1C, but has an opposite effect on Channel function (PubMed: 15140941).

Suppresses the calcium-dependent inactivation of CACNA1D (By similarity).

Inhibits TRPC5 Channels (PubMed: 15895247).

Prevents NMDA receptor-induced cellular degeneration.

Required for the normal transfer of light signals through the retina (By similarity).