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Human Serine palmitoyltransferase, long chain base subunit 2,SPTLC2 ELI
Price
3,140.00 ₪
Serine palmitoyltransferase (SPT).
The heterodimer formed with LCB1/SPTLC1 constitutes the catalytic core.
The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference.
The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC2-SPTSSB complex displays a preference for C18-CoA substrate.
Plays an important role in de novo sphyngolipid biosynthesis which is crucial for adipogenesis (By similarity).
{ECO:0000250|UniProtKB:P97363, ECO:0000269|PubMed:19416851, ECO:0000269|PubMed:19648650, ECO:0000269|PubMed:20920666}.
Quantity
Storage and Stability
2-8ºC
Sensitivity
0.13ng/ml
Detection range
0.25-16ng/ml
Shipping Conditions
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