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Human Serine;threonine-protein phosphatase PGAM5, mitochondrial,PGAM5 ELI
Price
3,140.00 ₪
Displays phosphatase activity for serine/threonine residues, and, dephosphorylates and activates MAP3K5 kinase.
Has apparently no phosphoglycerate mutase activity.
May be regulator of mitochondrial dynamics.
Substrate for a KEAP1-dependent ubiquitin ligase complex.
Contributes to the repression of NFE2L2-dependent gene expression.
Acts as a central mediator for programmed necrosis induced by TNF, by reactive oxygen species and by calcium ionophore.
{ECO:0000269|PubMed:18387606, ECO:0000269|PubMed:19590015, ECO:0000269|PubMed:22265414}.
Quantity
Storage and Stability
2-8ºC
Sensitivity
0.25ng/ml
Detection range
0.5-32ng/ml
Shipping Conditions
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