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Human Single Ig IL-1-related receptor,SIGIRR;TIR8 ELI
Price
3,140.00 ₪
Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways.
Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4.
Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP.
{ECO:0000269|PubMed:12925853, ECO:0000269|PubMed:14715412, ECO:0000269|PubMed:15866876, ECO:0000269|PubMed:25963006}.
Quantity
Storage and Stability
2-8ºC
Sensitivity
0.28ng/ml
Detection range
0.5-200ng/ml
Shipping Conditions
Next Day Ambient
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