Human Sodium Channel Protein Type 10 Subunit Alpha, SCN10A ELI

Tetrodotoxin-resistant channel that mediates the voltage-dependent sodium ion permeability of excitable membranes.

Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient.

Plays a role in neuropathic pain mechanisms.