Human Sodium Channel Protein Type 8 Subunit Alpha, SCN8A ELI

Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient.In macrophages and melanoma cells, may participate in the control of podosome and invadopodia formation.