Human Solute Carrier Family 2, Facilitated Glucose Transporter Member 2, SLC2A2

Facilitative hexose transporter that mediates the transport of glucose and fructose (PubMed: 8027028, PubMed: 16186102, PubMed: 23396969, PubMed: 28083649).

Likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell (PubMed: 8027028).

May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney (PubMed: 3399500).

Also able to mediate the transport of dehydroascorbate (PubMed: 23396969).