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Human Sorbin and Sh3 Domain-containing Protein 2, SORBS2 ELI

Price

‏3,140.00 ‏₪

Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton.

Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1.

May play a role in the regulation of pancreatic cell adhesion, possibly by acting on WASF1 phosphorylation, enhancing phosphorylation by ABL1, as well as dephosphorylation by PTPN12 (PubMed:18559503). Isoform 6 increases water and sodium absorption in the intestine and gall-bladder.

Package Size

Quantity

Storage and Stability

2-8ºC

Sensitivity

9.81ng/L

Detection range

20-4500ng/L

Shipping Conditions

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