Human Sulfhydryloxidase 1, QSOX1 ELI

Catalyzes the oxidation of sulfhydryl groups in Peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide (PubMed: 17331072, PubMed: 18393449, PubMed: 23704371, PubMed: 30367560, PubMed: 23867277).

Plays a role in disulfide bond formation in a variety of extracellular proteins (PubMed: 17331072, PubMed: 30367560, PubMed: 22801504, PubMed: 23867277).

In fibroblasts, required for normal incorporation of laminin into the extracellular matrix, and thereby for normal cell-cell adhesion and cell migration (PubMed: 23704371, PubMed: 30367560, PubMed: 23867277).