Human Synaptotagmin 1,SYT1 ELI
3,140.00 ₪
Calcium sensor that participates in triggering neurotransmitter release at the synapse (By similarity).
May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse (By similarity).
It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported.
It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2.
Plays a role in dendrite formation by melanocytes (PubMed:23999003).
{ECO:0000250|UniProtKB:P46096, ECO:0000269|PubMed:23999003}.
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