Human Syntaxin 4, STX4 ELI

Plasma membrane t-SNARE that mediates docking of transport vesicles.

Necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane.

Together with STXB3 and VAMP2, may also play a role in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes (By similarity). May also play a role in docking of synaptic vesicles at presynaptic active zones.