Human thyrotropin-releasing hormone,TRH ELI

As a component of the hypothalamic-pituitary-thyroid axis, it controls the secretion of thyroid-stimulating hormone (TSH) and is involved in thyroid hormone synthesis regulation.

It also operates as modulator of hair growth.

It promotes hair-shaft elongation, prolongs the hair cycle growth phase (anagen) and antagonizes its termination (catagen) by TGFB2.

It stimulates proliferation and inhibits apoptosis of hair matrix keratinocytes.

{ECO:0000269|PubMed:19825978}.