top of page
Human TNF-related apoptosis-inducing ligand receptor 1,TRAIL-R1 ELI
Price
3,140.00 ₪
Receptor for the cytotoxic ligand TNFSF10/TRAIL (PubMed:26457518).
The adapter molecule FADD recruits caspase-8 to the activated receptor.
The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis (PubMed:19090789).
Promotes the activation of NF-kappa-B (PubMed:9430227).
{ECO:0000269|PubMed:19090789, ECO:0000269|PubMed:9430227}.
Quantity
Storage and Stability
2-8ºC
Sensitivity
0.21ng/ml
Detection range
0.38-24ng/ml
Shipping Conditions
Next Day Ambient
bottom of page