Human Translationally-controlled Tumor Protein, TPT1 ELI

Translationally Controlled Tumor Protein (TCTP) is a protein that in humans is encoded by the TPT1 gene.

The TPT1 gene is mapped 13q12-q1413 in the Chromosome 13.

The human gene contains five introns and six exons, The TPT1-gene contains a promoter with a canonical TATA-box and several promoter elements, which are well-conserved in mammals.

The assay with reporter gene exhibits a strong promoter activity comparable to viral promoters.

The abundance and ubiquity indicate that TCTP may have important primary functions.

However, a large number of cellular and biochemical functions have been found since 1980s.

Most of these functions can be classified into three groups.