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Human Transmembrane prolyl 4-hydroxylase,P4HTM ELI
Price
3,140.00 ₪
Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins.
Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'.
May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.
{ECO:0000269|PubMed:17726031}.
Quantity
Storage and Stability
2-8ºC
Sensitivity
0.09ng/ml
Detection range
0.19-12ng/ml
Shipping Conditions
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