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Human Tumor necrosis factor-associated factor 1,TRAF1 ELI

Price

‏3,140.00 ‏₪

Adapter molecule that regulates the activation of NF-kappa-B and JNK.

Plays a role in the regulation of cell survival and apoptosis.

The heterotrimer formed by TRAF1 and TRAF2 is part of a E3 ubiquitin-protein ligase complex that promotes ubiquitination of target proteins, such as MAP3K14.

The TRAF1/TRAF2 complex recruits the antiapoptotic E3 protein-ubiquitin ligases BIRC2 and BIRC3 to TNFRSF1B/TNFR2.

{ECO:0000269|PubMed:10692572, ECO:0000269|PubMed:16323247, ECO:0000269|PubMed:18429822, ECO:0000269|PubMed:19287455, ECO:0000269|PubMed:19698991, ECO:0000269|PubMed:20385093}.

Package Size

Quantity

Storage and Stability

2-8ºC

Sensitivity

9.29ng/L

Detection range

20-4500ng/L

Shipping Conditions

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