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Human V-type proton ATPase 116 kDa subunit a isoform 2,ATP6V0A2 ELI

Price

‏3,140.00 ‏₪

Part of the proton channel of V-ATPases.

Essential component of the endosomal pH-sensing machinery.

May play a role in maintaining the Golgi functions, such as glycosylation maturation, by controlling the Golgi pH.

In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (PubMed:28296633).

{ECO:0000269|PubMed:16415858, ECO:0000269|PubMed:18157129, ECO:0000269|PubMed:28296633}.

Package Size

Quantity

Storage and Stability

2-8ºC

Sensitivity

9.13ng/L

Detection range

20-4500ng/L

Shipping Conditions

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