top of page

Human Vitamin D Receptor,VDR ELI

Price

‏3,140.00 ‏₪

Nuclear receptor for calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells (PubMed:28698609, PubMed:16913708, PubMed:15728261, PubMed:10678179).

Enters the nucleus upon vitamin D3 binding where it forms heterodimers with the retinoid X receptor/RXR (PubMed:28698609).

The VDR-RXR heterodimers bind to specific response elements on DNA and activate the transcription of vitamin D3-responsive target genes (PubMed:28698609).

Plays a central role in calcium homeostasis (By similarity).

{ECO:0000250|UniProtKB:P13053, ECO:0000269|PubMed:10678179, ECO:0000269|PubMed:15728261, ECO:0000269|PubMed:16913708, ECO:0000269|PubMed:28698609}.

Package Size

Quantity

Storage and Stability

2-8ºC

Sensitivity

7.33ng/L

Detection range

15-3000ng/L

Shipping Conditions

Next Day Ambient
bottom of page